
Mixed-Use Land for Sale in Palmetto, Florida
5405 US Highway 19, Palmetto, FL 34221
1.398 Acres MOL, Partially-Cleared, Vacant Lot opportunity with an ample 300 feet of Frontage located along US Highway 19 in lovely Palmetto, Florida. Northbound access is available via Median Opening. As per Utilities: A 12-inch Diameter Water Line is located across US 19. A 8-inch Diameter Sewer Line is located along the West side of Parcel. Palmetto is strategically positioned midway between Tampa / St. Petersburg to the north and Sarasota to the south, placing it in the heart of Florida’s rapidly expanding Gulf Coast growth corridor. The surrounding area features a strong mix of existing and under-construction residential communities, including waterfront estates, golf and country club neighborhoods, and thoughtfully designed master-planned developments. The site offers excellent accessibility, with convenient proximity to I-75, providing seamless connectivity to major employment centers, retail hubs, and regional amenities. With continued residential expansion and strong regional demand, this location presents an exceptional opportunity for residential or mixed-use development in one of Southwest Florida’s most active growth markets. Said Frontage, coupled with a Lot Depth measuring 203 feet and NCM RSF6 Zoning Classification (therefore allowing for Neighborhood Commercial Mixed Use & Six Residential Units per Acre) allows a plethora of options in determining highest & best use by its future Owner. (Neighborhood Commercial - Medium District) allows multiple retail uses, personal services and offices to serve existing residential neighborhoods. Permitted uses allowed are as follows: - Adult Day Care Center - Agricultural Uses - Alcoholic Beverage Establishment - 2 COP License - Animal Services (Wild and Exotic) - Assisted Living Facility, Large - Assisted Living Facility, Small - Banking: Bank - Banking: Bank/Drive-through - Bed and Breakfast - Bus and Train Passenger Station - Business Services - Car Wash: Incidental - Cemetery: Human and Pet - Child Care Center, Accessory - Child Care Center, Large - Child Care Center, Small - Churches/Places of Worship - Civic, Social, and Fraternal Organizations/Clubs - Clinics - Community Residential Homes - Cultural Facilities - Drive-Through Establishments - Dry Cleaners: General - Dry Cleaners: Pick-Up - Earthmoving, Minor - Environmental Land Preserves, Public and Private - Food Catering Service Establishment - Funeral Chapel - Funeral Home - Lodging Places: Boarding House - Lodging Places: Hospital Guest House - Medical Marijuana Treatment Center Dispensing Facility - Miscellaneous Services: Office - Nursing Homes - Office, Medical or Professional - Parking, Commercial (Principal Use) - Personal Service Establishment - Post Offices – Printing. Feel free to reach out with absolutely any questions & thanks for looking!
Location
- Street address
- 5405 US Highway 19
- County
- Manatee County
- Elevation
- 3 feet
Directions
Traveling upon Interstate 75 South towards Naples (I-75 S (SR-93A)), Take Exit 228 toward St Petersburg onto I-275 N (SR-93), Take Exit 2 toward US-41 S/Palmetto/Bradenton, Turn Left onto US-41 N (US-41 S), Turn Right onto 49th Street E, Turn Right onto US Highway 19 (US-19 N), Make a U-Turn onto US Highway 19 (US-19 S), Property will be located on your Right in <0.1 miles.
Property details
- Acreage
- 1.39 acres
- Zoning
- NCM RSF6
- MLS #
- MFRMLS TB8384829
- Posted
Property taxes
- 2024
- $2,293
Parcels
- 22049-0000-1
Resources
Details and features
Listing
- Type
- Land
Exterior
- Features
- Level
Nearby schools
| Name | Type |
|---|---|
| Palm View Elementary | Elementary |
| Lincoln Middle | Middle |
| Palmetto High | High |
Listing history
| Date | Event | Price | Change | Source |
|---|---|---|---|---|
| May 14, 2025 | New listing | $329,000 | — | MFRMLS |


























