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Land with Home for Sale in Defiance, Missouri

2275 Highway F, Defiance, MO 63341

$3,450,000
22 acres
Active sale
ago
Est $20,068/mo

Imagine owning a timeless piece of Missouri history. More than 250 years ago, the Osage people traveled these valleys, and pioneers like Daniel Boone, his son Nathan and nephew/adopted son Jonathan Bryan helped shape this remarkable landscape. A captivating driveway leads around to a ONE-OF-A-KIND property built in the 1840's for Jonathan Bryan. "Bryan Mill" rests gracefully on 22+/- acres providing a peaceful & tranquil atmosphere, conveniently located near Augusta & Defiance, with a STRIKING, FINELY DETAILED, FULLY FURNISHED, FRENCH INSPIRED w/exquisite imported antiques curated by Annie Brahler of EuroTrash, Inc. At the heart of the property is an 1840s built cottage exquisitely reimagined as a luxurious country residence, and STATELY early 1800's built 68'x36' Stone mill/outbuilding with 2 BEAUTIFUL automatic solid wood doors, floor-to-ceiling Stone fireplace, 37'+/- vaulted ceiling, kitchen, 2 half baths, & an abundant amount of storage space, AND a COMPLETELY REDONE stone chicken coop. Throughout the cottage, historic details have been carefully preserved and complemented by modern mechanical systems, conveniences, and automated security and surveillance. The home boasts 2,815+/- SqFt, 5 bedrooms, 2 full baths, with mostly original hardwood flooring throughout and a kitchen anchored by a 65 inch La Cornue Chateau Series range. The historic mill is equally remarkable. Beautifully restored and fully climate-controlled with modern HVAC systems, the mill features a catering kitchen and expansive event and entertaining spaces. It offers an extraordinary setting for private dinners, celebrations, retreats, creative pursuits, or large-scale entertaining-all without ever leaving the privacy of the estate. Create a legacy where your children and grandchildren can reconnect with nature-plant gardens, raise animals, ride horses, explore miles of side-by-side trails, or simply enjoy the peace and beauty that only a property like this can offer. Beyond the residence, private acreage unfold through rolling fields, mature woods, gardens, and majestic private pathways winding throughout the estate. A dramatic boulder firepit creates an intimate destination for evenings outdoors, while even the custom chicken coop has been thoughtfully designed to complement the architecture and character of the property. Opportunities to own a tract with this combination of history, natural beauty, privacy, and location are exceptionally rare, especially with frontage on the coveted Hwy F. This isn't just land-it's a place where your family's next chapter can begin and memories can be made for generations to come. MUST SEE! *ALL PARTIES UNDERSTAND PROPERTY IS SUBJECT TO SURVEY AND APPROVED THROUGH CITY & ALL GOVERNMENTAL AUTHORITIES.* Additional acreage FOR SALE. See MLS #'s: 26053203 (LOT #2, 12.5+/- ACRES), 26053360 (LOT #3, 38.5+/- ACRES), & 26053204 (LOT #4, 32+/- ACRES).

2,815
Sq feet
5
Beds
2
Full baths
2
1/2 baths
1843
Built

Location

Street address
2275 Highway F, Lot 1
Zip code
63341
Community
Francis Howell CNTRL
School district
Francis Howell R-III
Elevation
575 feet
Coordinates
38.6651, -90.8698

Directions

From I-64 West, take exit 10 onto HWY 94 towards Defiance, turn Left onto HWY 94, turn Right onto HWY F, turn Right, property will be on your Right. See sign.

Property details

Acreage
22 acres
MLS #
MARIS 26053202
Posted

Parcels

  • 3-0141-0301-00-0002.1000000

Open houses

DateBeginsEndsAppt neededRemarks
Sept 15, 202611:00 AM3:00 PMNo

Details and features

Listing

Type
Residential
Subtype
Single Family Residence

Lot

Features
Cleared, Many Trees, Meadow, Pasture, Scattered Woods

Exterior

Pool
Patio, Porch
Features
Fire Pit, Private Entrance

Structure

Style
Colonial, French
Stories
3
Water
Well
Sewer
Septic Tank
Heating
Forced Air
Cooling
Central Air, Electric
Materials
Stone
Roof
Wood
Windows
Window Coverings

Interior

Room Count
9
Rooms
Basement, Bathroom x 4, Bedroom x 5
Fireplaces
Yes
Appliances
Built-In Freezer, Built-In Refrigerator, Dishwasher, Disposal, Gas Range, Range Hood, Tankless Water Heater, Washer/Dryer, Water Purifier
Security
Security System
Features
Beamed Ceilings, Built-In Features, Center Hall Floorplan, Chandelier, Eat-In Kitchen, Entrance Foyer, Natural Woodwork, Recessed Lighting, Smart Thermostat, Sound System, Vaulted Ceiling(s)

Property utilities

CategoryTypeStatus
WaterPublicAvailable

Nearby schools

NameTypeDistrict
Daniel Boone Elem.ElementaryFrancis Howell R-III
Francis Howell MiddleMiddleFrancis Howell R-III
Francis Howell Central HighHighFrancis Howell R-III

Listing history

DateEventPriceChangeSource
Sept 8, 2026New listing$3,450,000MARIS
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This 22-acre property is located at 2275 Highway F Lot 1 in Defiance, MO 63341. The property is available for sale, priced at $3,450,000. It has a 2,815 square foot 5-bedroom, 3-bath house built in 1843.

Listed by Tom Shaw, REALTORS, (636) 346-4960

Checked 1 hour agoUpdated Source

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