Commercial Land for Sale in St. Louis, Missouri

Northrup Business Center is a two-building, 40,124-square-foot industrial and flex assemblage situated on 2.24 contiguous acres at the signalized intersection of South Kingshighway Boulevard and Interstate 44, in the heart of St. Louis's historic Hill neighborhood. With approximately 19,896 square feet now available across both buildings, the property offers flexible, move-in-ready space for office, warehouse, flex, retail, food-service, or outdoor-storage users - leasable by individual suite or in combination to fit a range of space requirements. At 5017-5019 Northrup, roughly 4,000 square feet of second-floor office space is available immediately, positioned above ground-floor warehouse bays with 17-to-19-foot clear heights and 12-foot overhead roll-up doors serving each side of the building - ideal for a tenant needing office-over-warehouse configuration with dedicated drive-in loading. At 5025 Northrup, up to 15,896 square feet is available across several contiguous and stand-alone suites, including the former Go St. Louis and Preferred Family spaces plus an additional spec suite, inside an ADA-accessible, elevator-served building that has recently received a new roof over the majority of its footprint. The 5021 outbuilding on site includes an existing walk-in cooler and food-service buildout, offering an established use case for restaurant, catering, or food-production tenants looking to expand within The Hill. Both buildings benefit from 3-phase electric service and updated HVAC systems, and the 5025 site is fenced, landscaped, and offers curb-cut access on both its north and south sides. The property is zoned K - Unrestricted, permitting industrial, flex, office, retail, food-service, and outdoor storage (IOS) uses, giving tenants significant flexibility in how they build out and operate their space. The location offers exceptional visibility and access: the site fronts South Kingshighway Boulevard at its signalized interchange with I-44, one of the region's primary east-west arterials, with an estimated 38,000 vehicles passing daily and immediate onward connectivity to I-55 and I-64. Roof-signage rights provide direct highway exposure. The Hill is one of St. Louis's most recognizable neighborhoods, long known for its Italian-American food and restaurant culture, and the immediate corridor is anchored by a QT gas station and a U-Haul center next door - established highway-commercial demand drivers at the same intersection. For tenants seeking flexible industrial, flex, or office space with strong highway access and visibility in an established St. Louis neighborhood, Northrup Business Center offers a rare combination of location, flexibility, and use.